Compound Sodium Chloride Injection 500ml

【Drug Name】

Common Name: Compound Sodium Chloride Injection

Product name:Compound Sodium Chloride Injection

【Ingredients】 This product is a compound preparation, and its components are sodium chloride, potassium chloride and calcium chloride. The excipient is water for injection.

【Properties】 This product is a colorless clear liquid.

【indications】

(1) Loss of water caused by various reasons, including hypotonicity, isotonicity and hypertonic water loss;

(2) hyperosmolar non-ketotic coma, the application of isotonic or hypotonic sodium chloride can correct the water loss and hypertonic state;

(3) Low chloride metabolic alkalosis.

Sodium chloride injection or Compound Sodium Chloride Injection can be given when the patient is unable to eat or eat for a certain reason and needs to supplement the daily physiological requirements. Because this product contains very little potassium, hypokalemia needs to be supplemented as needed.

【Specification】 500ml

【Adverse reactions】

(1) too much infusion, too fast, can cause sodium retention, causing edema, elevated blood pressure, increased heart rate, chest tightness, difficulty breathing, and even acute left heart failure.

(2) inappropriately administered hypertonic sodium chloride can cause hypernatremia.

(3) too much, too fast to give hypotonic sodium chloride can cause hemolysis, brain edema and so on.

【taboo】

(1) Heart failure.

(2) pulmonary edema.

(3) cerebral edema, increased intracranial pressure.

(4) cirrhosis ascites.

(5) acute renal failure oliguria; chronic renal failure in response to poor diuretics.

(6) Hypernatremia.

【Precautions】

Use the following carefully:

(1) There is edema in pregnancy.

(2) High blood pressure.

(3) edema or edema tendency, high edema with hyponatremia should pay attention to.

(4) mild heart and kidney dysfunction.

(5) hypokalemia.

(6) Elderly people with reduced heart function.

(7) The administration should be based on the nature of hypertonic, isotonic or hypotonic, and the other solutions should be considered to maintain the balance between various electrolytes in the body.

(8) Follow-up examination of serum potassium, sodium, chlorine concentration, acid-base balance, heart, lung, kidney function, blood pressure and other indicators.

【Pregnant women and lactating women】The safety and efficacy of medication for pregnant women and lactating women has not been established.

【Children's medication】 The amount and speed of rehydration in children should be strictly controlled.

【Geriatric Use】 The amount and speed of rehydration in the elderly should be strictly controlled.

【drug interaction】

 (1) compatibility with amphotericin B, etc., turbidity or precipitation, discoloration; (2) contraindications with reserpine, polymyxin B sulfate, polymyxin E sulfate, cephalosporin I.

【Drug overdose】

Excessive infusion, too fast, can cause water, sodium retention, causing edema, elevated blood pressure, increased heart rate, chest tightness, difficulty breathing, and even acute left heart failure. Can cause hypernatremia, causing loss of bicarbonate.

【Pharmacology and Toxicology】

Compound sodium chloride is a body fluid supplement and a drug that regulates the balance of water and electrolytes. It contains water for injection, Na + and Cl - ions and a small amount of K + and Ca 2+ ions. Na +and Cl - are important electrolytes in the body, mainly in extracellular fluids, and play an important role in maintaining the normal blood and extracellular fluid volume and osmotic pressure. Normal blood Na +concentration is 135 ~ 145mmol / L, accounting for 92% of plasma cations, 90% of total osmotic pressure, so plasma Na + amount plays a decisive role in osmotic pressure. CI normal serum - concentration of 98 ~ 106mmol / L. The human body is mainly regulated by the hypothalamus, the posterior pituitary and the kidney to maintain the stability of body fluid volume and osmotic pressure. In addition to the above effects, the compound sodium chloride can also be supplemented with a small amount of potassium ions and calcium ions.

【Pharmacokinetics】 Chlorine, sodium, potassium and calcium ions are mainly excreted by the regulation of the kidney after intravenous injection.

【Storage】 shading, confined storage.

【Packing】 non-PVC soft bag [easy folding (double valve)], 500ml / bag × 20 bags.

【Validity Period】 24 months

【Executive Standards】 "Chinese Pharmacopoeia" 2015 Edition 2

【Approval No.】 National Drug Standard H20113239

【Manufacturer】

Company Name: Zhejiang Kancheer Pharmaceutical Co., Ltd.

Production address: Beijiang Industrial Zone, Geshan Town, Dongyang City, Zhejiang Province, China

Website: www.tianshicheng.cn

Zip code: 322105

Tel: (0579) 86019696 86019610

Fax number: (0579) 86019611